INDIGO Announces In Vitro Toxicology Platform featuring upcyte human hepatocytes

New Product Families

(Go to INDIGO Biosciences Inc website for more information)

  • Dog PXR
  • Mouse PXR
  • Monkey PXR
  • Mouse RORɣ
  • Human LRH-1

New Screening Services

(Go to INDIGO Biosciences Inc website for more information)

  • Study species differences in PXR activation with human, monkey, dog, mouse and rat orthologs. 
  • In vitro toxicity and gene expression services
  • Mouse RORɣ
  • Human LRH-1

What's New at NRR?

Added a White Paper “Species Differences in PXR activation” in Education

Added LRH-1 (NR5A2) page to NR Page Collection

Several new review articles are psoted in the “Educational tab” including:

  • Gene Expression: General Concepts
  • Examining dose-response relationships
  • Nuclear receptors and gene expression
  • Nuclear receptors and gene expression in liver

As a result of these activities, there are several new images and pathways in the “Drawings” tab

Welcome to the Nuclear Receptor Resource website, dedicated to this important family of ligand-activated transcription factors. On these pages you will find some articles and reviews about various nuclear receptors (NRs). Nuclear Receptor News (NRN)  is a quarterly newsletter put out by the editors of this website and will highlight a new receptor each issue. The NRs Page Collection will be a starting point to find more information on each of the 48 human nuclear receptors. Go to the Site Map to see the full complement of pages available.