ABSTRACT

Blackcurrants (Ribes nigrum L., Grossulariaceae) contain high amounts of anthocyanin polyphenols, which have antioxidant and anti-carcinogenic health benefits. This study analyzed the potential phytoestrogenic effects of blackcurrant extract (BCE) in breast cancer (MCF-7) and human endometrial cancer (Ishikawa) cell lines that over-express estrogen receptor alpha (ERα), as well as in immature female rats.

To read the full article click HERE.

Date of publication: 13 October 2015; Molecular Nutrition & Food Research

Author information: Naoki Nanashima (1); Kayo Horie (2); Toshiko Tomisawa (3); Mitsuru Chiba (1); Manabu Nakano (1); Toshifumi Fujita (4); Hayato Maeda (5); Maiko Kitajima (2); Shizuka Takamagi (4); Daishi Uchiyama (6); Jun Watanabe (2); Toshiya Nakamura (1); & Yoji Kato (7)

(1) Department of Biomedical Sciences, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan
(2) Department of Pathologic Analysis, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan
(3) Department of Health Promotion, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan
(4) Department of Disability and Health, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan
(5) Faculty of Agriculture and Life Science, Hirosaki University, Hirosaki, Japan
(6) Center for Joint Research, Hirosaki University, Hirosaki, Japan
(7) Faculty of Education, Hirosaki University, Hirosaki, Japan

Tagged With: