| URN | urn:agi-llid:6820 |
|---|---|
| Name | SULT2B1 |
| Description | sulfotransferase family, cytosolic, 2B, member 1 |
| Connectivity | 16 |
| Notes | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq] |
| Swiss-Prot Accession | O00204 |
|---|---|
| O35400 | |
| Q29YR5 |
| Unigene ID | Hs.369331 |
|---|---|
| Mm.271634 | |
| Rn.100005 |
| KEGG ID | mmu:54200 |
|---|---|
| rno:292915 |
| EC Number | 2.8.2.2 |
|---|
| Swiss-Prot ID | ST2B1_HUMAN |
|---|---|
| ST2B1_MOUSE | |
| ST2B1_RAT |
| Cell Localization | Mitochondria |
|---|
| GO ID | 0004027 |
|---|---|
| 0050294 | |
| 0016740 | |
| 0006629 | |
| 0008202 | |
| 0005737 | |
| 0005829 | |
| 0008146 | |
| 0000103 |
| Pathway | Toxicology Array |
|---|---|
| New Pathway | |
| PPARalpha Pathway |
| IPI ID | IPI00008179 |
|---|---|
| IPI00328142 | |
| IPI00130613 | |
| IPI00322602 | |
| IPI00831322 | |
| IPI00768725 | |
| IPI00393341 |
| Ariadne Ontology | Steroid metabolism |
|---|
| Mouse chromosome position | 7 B4 |
|---|
| GO Molecular Function | transferase activity |
|---|---|
| sulfotransferase activity | |
| steroid sulfotransferase activity | |
| alcohol sulfotransferase activity |
| Homologene ID | 49487 |
|---|
| Hugo ID | 11459 |
|---|
| GO Cellular Component | cytoplasm |
|---|---|
| cytosol |
| MGI ID | 1926342 |
|---|
| Human chromosome position | 19q13.3 |
|---|
| GO Biological Process | steroid metabolic process |
|---|---|
| sulfate assimilation | |
| lipid metabolic process |
| Rat chromosome position | 1q22 |
|---|
| Group | Steroid metabolism |
|---|---|
| cytoplasm | |
| cytosol | |
| transferase activity | |
| sulfotransferase activity | |
| steroid sulfotransferase activity | |
| alcohol sulfotransferase activity | |
| steroid metabolic process | |
| sulfate assimilation | |
| lipid metabolic process |
| RGD ID | 1308882 |
|---|
| LocusLink ID | 6820 |
|---|---|
| 54200 | |
| 292915 |
| Alias | HSST2 |
|---|---|
| sulfotransferase family, cytosolic, 2B, member 1 | |
| SULT2B | |
| AI326997 | |
| BB173635 | |
| OTTMUSP00000025742 | |
| hydroxysteroid sulfotransferase | |
| cytosolic sulfotransferase family, 2B, member 1 isoform a | |
| Hydroxysteroid sulfotransferase HSST2B | |
| sulfotransferase family 2B, member 1 | |
| sulfotransferase family, cytosolic, 2B, member 1 isoform a | |
| Sult-x1 | |
| Sult-x2 | |
| sulfotransferase-related protein SULT-X I | |
| cytosolic sulfotransferase family, 2B, member I | |
| sulfotransferase family 2B, member I | |
| cytosolic sulfotransferase family, 2B, member 1 | |
| sulfotransferase family, cytosolic, 2B, member I | |
| Sult2b I | |
| Sult-x I | |
| Sult2b1 |
| Organism | Homo sapiens |
|---|---|
| Mus musculus | |
| Rattus norvegicus |
| OMIM ID | 604125 |
|---|