These pages were made using Pathway Studio (Ariadne Genomics). The NRs are listed in the Nomenclature Table. Follow the link to go to an external, interactive webpage. To explore the target gene, simply click on the protein name and you will see a summary information. If you are interested in the association between a NR and another protein, find the midpoint symbol on the arrow (a box the same color as the link), click and the type of relationship and references will be shown. There is a lot of interesting information on each map, so explore!
Nuclear Receptor Pathway Data
Group |
Genes |
Trivial Names |
Target Genes |
Interactions |
1A |
NR1A1 |
TRa, c-erbA-1, THRA |
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NR1A2 |
TRb, c-erbA-2, THRB |
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1B |
NR1B1 |
RARa |
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NR1B2 |
RARb, HAP |
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NR1B3 |
RARg, RARD |
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1C |
NR1C1 |
PPARa |
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NR1C2 |
PPARb, NUC1, PPARd, FAAR |
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NR1C3 |
PPARg |
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1D |
NR1D1 |
REVERBa, EAR1, EAR1A |
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NR1D2 |
REVERBb, EAR1b, BD73, RVR, HZF2 |
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1F |
NR1F1 |
RORa, RZRa |
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NR1F2 |
RORb, RZRb |
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NR1F3 |
RORg, TOR |
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1H |
NR1H2 |
UR, OR-1, NER1, RIP15, LXRb |
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NR1H3 |
RLD1, LXR, LXRa |
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NR1H4 |
FXR, RIP14, HRR1 |
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1I |
NR1I1 |
VDR |
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NR1I2 |
ONR1, PXR, SXR, BXR |
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NR1I3 |
MB67, CAR1, CARa |
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CAR3 (splice variant) |
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2A |
NR2A1 |
HNF4 |
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NR2A2 |
HNF4G |
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2B |
NR2B1 |
RXRA |
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NR2B2 |
RXRB, H-2RIIBP, RCoR-1 |
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Click |
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NR2B3 |
RXRG |
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Click |
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NR2B4 |
USP, Ultraspiracle, 2C1, CF1, RXR1, RXR2 |
Click |
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2C |
NR2C1 |
TR2, TR2-11 |
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2E |
NR2E1 |
TLL, TLX, XTLL |
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NR2E3 |
PNR |
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2F |
NR2F1 |
COUP-TFI, COUPTFA, EAR3, SVP44 |
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NR2F2 |
COUP-TFII, COUPTFB, ARP1, SVP40 |
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NR2F6 |
EAR2 |
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3A |
NR3A1 |
ERa |
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NR3A2 |
ERb |
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3B |
NR3B1 |
ERR1, ERRa |
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NR3B2 |
ERR2, ERRb |
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NR3B3 |
ERR3, ERRg |
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3C |
NR3C1 |
GR |
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NR3C2 |
MR |
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NR3C3 |
PR |
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NR3C4 |
AR |
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4A |
NR4A1 |
NGFIB, TR3, N10, NUR77, NAK1 |
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NR4A2 |
NURR1, NOT, RNR1, HZF-3, TINOR |
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NR4A3 |
NOR1, MINOR |
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5A |
NR5A1 |
SF1, ELP, FTZ-F1, AD4BP |
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NR5A2 |
LRH1, xFF1rA, xFF1rB, FFLR, PHR, FTF |
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6A |
NR6A1 |
GCNF1, RTR |
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0B |
NR0B1 |
DAX1, AHCH |
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NR0B2 |
SHP |
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