by Marketing | Mar 13, 2016 | New Publications
ABSTRACT Lots of experimental and clinical evidences indicate that chronic exposure to saturated fatty acids and high level of glucose is implicated in insulin resistance, beta cell failure and ultimately type 2 diabetes. In this study, we set up cell-based...
by Marketing | Feb 15, 2016 | New Publications
ABSTRACT Diabetes mellitus is a chronic metabolic disorder that affects more than 180 million people worldwide. Peroxisome proliferator activated receptors (PPARs) are a group of nuclear receptors that have been targeted by the thiazolidinedione (TZD) class of...
by Marketing | Dec 1, 2015 | New Publications
ABSTRACT Background: A systems toxicology investigation comparing and integrating transcriptomic and proteomic results was conducted to develop holistic effects characterizations for the wildlife bird model, Northern bobwhite (Colinus virginianus) dosed with the...
by Marketing | Jun 1, 2015 | New Publications
SIG1191 dose-response analysis of the human PPARγ (ligand-dependent transcription factor) activity was performed using INDIGO Biosciences’ luciferase reporter cells and compared to rosiglitasone as reference agonist ligand. ABSTRACT Isoprenylcysteine compounds...
by Marketing | Mar 27, 2015 | New Publications
ABSTRACT Activation of peroxisome proliferator-activated receptors (PPARs) has been shown to have an important role in skin barrier function by regulating differentiation and lipid synthesis in keratinocytes. Oat (Avena sativa) has long been used as a soothing agent...
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